Anne Lopes, co-founder of Meet-U, UPSUD - UPSaclay referent, Maître de Conférences in Biology. Her research work at the Institute of Integrative Biology of the Cell (I2BC) consists in deciphering the mechanisms underlying the functioning and evolution of biological systems. She chose to apprehend biological systems by focusing on the functioning and the evolution of proteins and of their interactions. Her projects aim at characterizing the 3D structure of proteins and their interactions by molecular modeling approaches integrating evolutionary information.
	Elodie Laine, co-founder of Meet-U, UPMC referent, Maître de Conférences in Biology. Her research activities at the laboratory of Computational and Quantitative Biology (LCQB) concern protein evolution, structural dynamics, interactions and allosteric regulation. She develops methods to predict mutational outcomes, protein-protein interactions and alternative splicing induced changes at large scale.
	Jean-Christophe Gelly, Univ. Paris-Diderot referent, Maître de Conférences, co-director of Master 2 Computational Biology and Bioinformatics at Univ. Paris Diderot. He conducts his research activity in "Dynamique des Structures et Interactions des Macromolécules Biologiques (DSIMB)" team. He develops and uses computational methods to understand protein sequence-structure-function-evolution relationships for analysis, prediction and design.
	Gaëlle Lelandais, in charge of collaborative work managment, Professor in Biology at UPSUD - UPSaclay. She teaches statistics, bioinformatics and functional genomics. Her research activities are linked to functional genomics and the characterization of transcriptional regulation networks, by exploiting experimental « high-thoughput » data (genomics, transcriptomics, proteomics).
	Arnaud Ferré, in charge of project managment teaching, PhD student in artificial intelligence for life sciences between the MaIAGE unit of INRA in Jouy-en-Josas and the laboratory LIMSI of CNRS. His research activities concern the extraction and automated formalisation of knowledge from scientific publications in Biology. He also has been developing skills in project managment and entrepreneurship.
	Guillaume Bouvier, students supervision, Researcher in the Structural Bioinformatics Unit at Institut Pasteur. His research deals with the study of protein conformational dynamics. He uses techniques based on purely theoretical aspects or on experimental data. Due to the diversity of the data being used, his domain of research is linked to integrative structural biology.
	Romain Coppée, students supervision, PhD Student in Genomic and Structural Bioinformatics at the University Paris-Descartes – UMR216. His work focuses on protein-coding genes implied in the resistance of various antimalarial treatments. He uses genomic information during species evolution combined with structural folding to measure the constraint level at each amino acid / codon site, and to highlight key amino acid residues (functional sites).
	Chloé Dequeker, students supervision, PhD student at the laboratory of Computational and Quantitative Biology (LCQB). She works on the characterization of protein-protein interactions. She analyses data obtained by docking algorithms and by algorithms that predict interaction sites between proteins. These data are used to discriminate cellular partners from non-interactors.
	Charlotte Périn, students supervision, PhD student at DSIMB (Dynamics and Simulations of Biological Molecules). She develops methods that predict proteins structures and for rational protein design. She also studies the links between sequence and structure.
	Guillaume Postic, students supervision, post-doctoral fellow in Structural Bioinformatics at the Institute of Mineralogy, Materials Physics and Cosmochemistry (IMPMC). His current work focuses on the docking of small cyclic peptides on multimeric proteins. He has developed several algorithms and web resources dedicated to the analysis and prediction of globular and membrane protein structures.
	Hugues Richard, students supervision, Maître de Conférences in Engineering at UPMC. He works at the laboratory of Computational and Quantitative Biology (LCQB) and has participated in several international projects for the (re-)sequencing of genomes. He develops statistical methods for the functional analysis of high-throughput sequencing data (transcriptomics, variant annotation, metagenomics with MetaSub).
	Hugo Schweke, students supervision, PhD student at the Institute of Integrative Biology of the Cell (I2BC). His research work is linked to the study of protein functioning. He is more specifically interested in the interactions proteins engage between them, which he studies with molecular docking methods.

Formations Universitaires Participantes

	Univ Paris-Sud - Univ Paris-Saclay Master de Bioinformatique Parcours AMI2B, Paris-Sud Christine Froidevaux & Olivier Lespinet
	Université Paris Diderot Spécialité Biologie Informatique Catherine Etchebest & Jean-Christophe Gelly
	Université Pierre et Marie Curie (UPMC) Spécialité Bioinformatique et Modélisation Master Biologie Moléculaire et Cellulaire Stéphane Le Crom & Philippe Lopez Master d'Informatique Alessandra Carbone & Martin Weigt

Acknowledgements

We thank the French Institute of Bioinformatics, which provided access to its Cloud to the participating teams and some technical support.